Principal Data Science Engineer - AI/ML & Algorithms

Job Description:

Please note that this position is not available for visa sponsorship, and we are unable to take over existing employment visa sponsorships

POSITION SUMMARY

We are currently seeking a talented and driven Principal Data Science Engineer - AI/ML & Algorithms, to join our team.  The Principal Data Science Engineer  will have the opportunity to develop intelligent, data-driven solutions to improve patient outcomes and clinical workflows by contributing to the life cycle of embedded and digital clinical software applications that monitor, control and preserve donated hearts, lungs, livers, and other organs on the OCS.

RESPONSIBILITIES

This position is responsible for, but not limited to, the following:

• End-to-end lifecycle of data-driven software products from data exploration and model development to deployment and regulatory compliance
• Data-driven model and algorithm development
• Design, train, and validate machine learning and traditional algorithms for clinical decision support and automation
• Ensure all data handling adheres to strict regulatory standards, including HIPAA and GDPR
• Work collaboratively with clinical leads, software engineers, and product teams to translate clinical needs into technical specifications and data solutions
• Implement data anonymization, pseudonymization, and secure access controls to protect sensitive patient information
• Guide clinical algorithmic strategy, perform reviews, and set best practices for development and validation
• Explain clinical algorithmic strategy and complex technical concepts to non-technical stakeholders
• Perform other TransMedics tasks and duties as assigned/required.

MANAGEMENT RESPONSIBILITIES

This position manages the following positions on a daily basis.

• This position will not have management responsibilities.

PHYSICAL ATTRIBUTES

• General Office Environment
• Ability to lift up to 25 lbs.
• May travel up to 10% domestically / 10% internationally

MINIMUM QUALIFICATIONS

• BS/MS in Computer Science, Data Science, Engineering, Mathematics, or an equivalent combination of education and experience. 
• 3+ years of relevant professional experience building and deploying machine learning solutions, with specific experience in an ML engineering or data science role.
• 8+ years of overall software development experience

PREFERRED QUALIFICATIONS

• Proven experience designing, developing, and deploying AI/ML models in a professional setting, with specific experience in the healthcare or life sciences industry preferred.
• Experience in applying AI/Machine Learning to practical uses.
• Expertise in Python, including standard ML and data science libraries like scikit-learn, NumPy, and pandas.
• Knowledge and hands-on experience with machine learning frameworks such as PyTorch.
• Strong foundation in linear algebra, calculus, probability, and statistical modeling.
• Proficiency in data manipulation, cleaning, and preprocessing techniques, as well as knowledge of SQL and NoSQL databases.
• Experience with AWS data engineering services for ETL, data processing, and end-to-end development, deployment, and management of ML models.
• Solid understanding of software development principles, including data structures, algorithms, and software architecture.
• Excellent analytical and critical thinking skills to tackle complex, multi-layered data challenges.
• Ability to clearly explain technical concepts to both technical and non-technical stakeholders.
• Ability to work with the engineering and leadership teams on the functional design, process design, prototyping, testing, and training of AI/ML solutions.
• Understanding of data privacy regulations like HIPAA, GDPR is a plus.
• Knowledge of medical device software development with compliance to IEC-62304 and FDA guidelines is a plus.
• Experience in C/C++ programming language is a plus
• Must be team-oriented with outstanding interpersonal and communication skills (written and verbal). 
• Must be detail-oriented and highly organized.

Every Organ Wasted is a Life Not Saved.

TransMedics, Inc. is a commercial-stage medical technology company transforming organ transplant therapy for patients worldwide. Our mission is to help save more patients’ lives by increasing access to viable donor organs for those who are awaiting an organ transplant. To accomplish this mission, we partner closely with transplant stakeholders worldwide and help expand their access to healthy donor organs, while delivering the highest quality technology, service, clinical care and outcomes.

Driven by a passion for improving patient care, we make the impossible possible and keep our employees at the center of everything we do. Together, we strive to enhance the quality of life for transplant recipients and their families, fostering hope and healing in the journey toward better health.

Maximize your potential at TransMedics, Inc.

www.TransMedics.com

As part of our long-term growth plans, TransMedics is excited to announce our plan to relocate our headquarters (HQ) to Somerville, MA by 2028. We chose this location because we believe it is a place where innovation will thrive. Our new state-of-the-art headquarters is designed to support collaboration, creativity, and discovery. We believe this will be a place where we can continue to do things few thought possible in organ transplantation to help patients. Specific timing and role impact may vary.

TransMedics is committed to equitable and transparent compensation. The expected base salary range for this role is $174,500.00-$237,100.00 , which represents the company’s current good-faith estimate of compensation for this position. Actual salary will depend on factors such as, but not limited to, candidate experience, qualifications, skills, and the specific work location. This role may also be eligible for bonuses, equity, and a comprehensive benefits package (medical, dental, vision, retirement savings, paid time off, and wellness resources). We comply with all U.S. pay transparency laws and do not request or consider salary history.

Employee Benefit:

Medical with Health Reimbursement Account through Blue Cross/Blue Shield of MA

Dental

Vision

Healthcare Flexible Spending Account

Dependent Care Flexible Spending Account

Short Term Disability

Long Term Disability

401K Plan

Pet insurance

Employee Stock Purchase Plan

TransMedics is an equal opportunity employer and does not discriminate on the basis of race, color, religion, sex, national origin, marital status, age, disability or protected veteran status, or any other characteristic protected by law. We are committed to creating an inclusive environment for all employees.