Senior Systems Engineer, GXP Systems

The Role:

Joining Moderna means advancing mRNA science to transform medicine. Work with exceptional global teams on a broad pipeline and build a career that makes a real difference for patients.

Moderna is establishing a leading research, development, and manufacturing facility at Harwell to support onshore mRNA vaccine production for respiratory diseases in the UK.

This long term investment will create skilled jobs and strengthen collaboration with academic, NHS, and government partners. We welcome experts ready to help expand access to life saving vaccines.

This role sits at the intersection of digital, automation, and quality, driving the design and evolution of advanced laboratory instrumentation ecosystems.

You will shape how benchtop and enterprise systems connect into a unified, intelligent digital lab environment.

Working within the Digital Quality team, you will combine hands-on engineering expertise with strategic thinking to enable scalable, compliant, and future-ready laboratory operations.

Here’s What You’ll Do:

• Design, deploy, and manage a growing portfolio of benchtop instrumentation and enterprise laboratory systems supporting Quality Control laboratories, ensuring seamless integration with connected digital platforms.

• Own the full product lifecycle management of instrumentation software and systems, including validation, optimization, integration, support, maintenance, and version upgrades across platforms such as Thermo Omnic FTIR, HIAC Particle Counter, TOC, Thermo QuantStudio/3730, RAMAN TruScan, Chromeleon CDS, LogiLab SDMS and CFR Gateway, SoftMax Pro, MODA, and Labvantage LIMS/LES.

• Collaborate closely with internal and external business analysts, automation and software engineers, and the TCoE to deliver robust and scalable digital lab solutions.

• Translate complex system, equipment, and data integration requirements from Digital and Business teams into effective and compliant digital lab system implementations.

• Lead and support change control and regulatory documentation, including living documents, SOPs, work instructions, and knowledge base materials to ensure inspection readiness and compliance.

• Partner with digital stakeholders to validate and integrate systems into connected instrument pipelines, enabling future robotics, automation, and AI-driven capabilities across the laboratory landscape.

• Actively foster innovation by challenging existing processes and leveraging emerging technologies, including opportunities to integrate Generative AI and advanced digital solutions into laboratory workflows.

• Apply an operational excellence mindset to identify, design, and implement process improvements that enhance system performance, user experience, and business efficiency.

• Ensure GMP compliance is embedded in the design, delivery, and lifecycle management of all systems.

• Maintain a constant state of inspection readiness through strict adherence to internal quality policies, procedures, and training requirements.

• Serve as a digital quality subject matter expert during internal and external audits for the assigned system portfolio.

• Operate as a hands-on individual contributor within a fast-paced environment, defining new processes where none exist and collaborating effectively with expert peers.

• Maintain an on-site presence in Harwell, with potential travel between regional sites as required.

• Take on additional responsibilities as needed to support evolving business and technical priorities.

The key Moderna Mindsets you’ll need to succeed in the role:

• We digitize everywhere possible using the power of code to maximize our impact on patients.

• We act with dynamic range, driving strategy and execution at the same time at every step.

Here’s What You’ll Need (Minimum Qualifications)

• Bachelor’s degree or equivalent in science, engineering or computer science

• 5 to 7+ years’ experience designing, implementing, and managing life sciences enterprise systems (CDS, SDMS, LIMS, ELN, LES) in a in biopharmaceutical GMP environment

• Direct experience with automation solutions such as Hamilton Venus preferred

• Experience with GAMP and GxP compliance regulations

• Experience in laboratory systems including data integrity regulations, instrument integration and laboratory digital workflow optimization

• Experience working with Digital systems hosted in cloud and understanding of connectivity between on-prem systems and SAAS/Cloud.

Here’s What You’ll Bring to the Table (Preferred Qualifications)

• Creative/innovative/problem solver that actively drives progress

• Ability to work independently and make sound and timely decisions to achieve expected results

• Strong understanding of core laboratory systems, related processes, and quality management workflows

• Strong interpersonal skills with the ability to build successful professional working relationships

• Ability to participate on multiple concurrent projects in a fast-paced environment.

• Ability to effectively collaborate in a dynamic, cross-functional matrix environment.

• A desire to make an impact as part of a high-growth, transformational company that is Bold, Relentless, Curious, and Collaborative.

Pay & Benefits

At Moderna, we believe that when you feel your best, you can do your best work.  That’s why our global benefits and well-being resources are designed to support you—at work, at home, and everywhere in between.

• Best-in-class healthcare, plus voluntary benefit programs to support your unique needs

• A holistic approach to well-being with access to fitness, mindfulness, and mental health support

• Family building benefits, including fertility, adoption, and surrogacy support

• Generous paid time off, including vacation, bank holidays, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown

• Savings and investments to help you plan for the future

• Location-specific perks and extras

The benefits offered may vary depending on the nature of your employment with Moderna and the country where you work.

About Moderna

Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.

By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.

We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.

As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact.

If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.

Moderna is a smoke-free, alcohol-free, and drug-free work environment.

Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!

Moderna is committed to equal opportunity in employment and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. We consider qualified applicants regardless of criminal histories, consistent with legal requirements.

We’re focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best.

Moderna is committed to offering reasonable accommodation or adjustments to qualified job applicants with disabilities. Any applicant requiring an accommodation or adjustment in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations and Adjustments team at [email protected].

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